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Development of hybrid monoliths incorporating metal–organic frameworks for stir bar sorptive extraction coupled with liquid chromatography for determination of estrogen endocrine disruptors in water and human urine samples

A novel coating based on hybrid monolith with metal–organic framework (MOF) onto conventional Teflon-coated magnetic stir bars was developed. For this purpose, the external surface of the Teflon stir bar was firstly vinylized in order to immobilize a glycidyl methacrylate (GMA)–based polymer onto th...

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Autores principales: Zatrochová, S., Martínez-Pérez-Cejuela, H., Catalá-Icardo, M., Simó-Alfonso, E. F., Lhotská, I., Šatínský, D., Herrero-Martínez, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821068/
https://www.ncbi.nlm.nih.gov/pubmed/35132465
http://dx.doi.org/10.1007/s00604-022-05208-6
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author Zatrochová, S.
Martínez-Pérez-Cejuela, H.
Catalá-Icardo, M.
Simó-Alfonso, E. F.
Lhotská, I.
Šatínský, D.
Herrero-Martínez, J. M.
author_facet Zatrochová, S.
Martínez-Pérez-Cejuela, H.
Catalá-Icardo, M.
Simó-Alfonso, E. F.
Lhotská, I.
Šatínský, D.
Herrero-Martínez, J. M.
author_sort Zatrochová, S.
collection PubMed
description A novel coating based on hybrid monolith with metal–organic framework (MOF) onto conventional Teflon-coated magnetic stir bars was developed. For this purpose, the external surface of the Teflon stir bar was firstly vinylized in order to immobilize a glycidyl methacrylate (GMA)–based polymer onto the magnet. Then, an amino-modified MOF of type MIL-101 (NH(2)-MIL-101(Al)) was covalently attached to the GMA-based monolith. After the synthesis process, several parameters affecting extraction of target estrogens by stir bar sorptive extraction (SBSE) including pH, ionic strength, extraction time, stirring rate, desorption solvent, and desorption time were also investigated. The resulting hybrid monolith was evaluated as SBSE sorbent for extraction of three estrogens (estrone, 17β-estradiol, estriol) and synthetic 17β-ethinylestradiol from water and human urine samples followed by HPLC with fluorescence detection (excitation and emission wavelengths, 280 and 310 nm, respectively). Under the optimal experimental conditions, the analytical figures of the method were established, achieving satisfactory limits of detection in the range of 0.015–0.58 µg L(−1), recovery results ranging from 70 to 95% with RSD less than 6%, and precision values (intra- and inter-extraction units) below 6%. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00604-022-05208-6.
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spelling pubmed-88210682022-02-23 Development of hybrid monoliths incorporating metal–organic frameworks for stir bar sorptive extraction coupled with liquid chromatography for determination of estrogen endocrine disruptors in water and human urine samples Zatrochová, S. Martínez-Pérez-Cejuela, H. Catalá-Icardo, M. Simó-Alfonso, E. F. Lhotská, I. Šatínský, D. Herrero-Martínez, J. M. Mikrochim Acta Original Paper A novel coating based on hybrid monolith with metal–organic framework (MOF) onto conventional Teflon-coated magnetic stir bars was developed. For this purpose, the external surface of the Teflon stir bar was firstly vinylized in order to immobilize a glycidyl methacrylate (GMA)–based polymer onto the magnet. Then, an amino-modified MOF of type MIL-101 (NH(2)-MIL-101(Al)) was covalently attached to the GMA-based monolith. After the synthesis process, several parameters affecting extraction of target estrogens by stir bar sorptive extraction (SBSE) including pH, ionic strength, extraction time, stirring rate, desorption solvent, and desorption time were also investigated. The resulting hybrid monolith was evaluated as SBSE sorbent for extraction of three estrogens (estrone, 17β-estradiol, estriol) and synthetic 17β-ethinylestradiol from water and human urine samples followed by HPLC with fluorescence detection (excitation and emission wavelengths, 280 and 310 nm, respectively). Under the optimal experimental conditions, the analytical figures of the method were established, achieving satisfactory limits of detection in the range of 0.015–0.58 µg L(−1), recovery results ranging from 70 to 95% with RSD less than 6%, and precision values (intra- and inter-extraction units) below 6%. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00604-022-05208-6. Springer Vienna 2022-02-07 2022 /pmc/articles/PMC8821068/ /pubmed/35132465 http://dx.doi.org/10.1007/s00604-022-05208-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Paper
Zatrochová, S.
Martínez-Pérez-Cejuela, H.
Catalá-Icardo, M.
Simó-Alfonso, E. F.
Lhotská, I.
Šatínský, D.
Herrero-Martínez, J. M.
Development of hybrid monoliths incorporating metal–organic frameworks for stir bar sorptive extraction coupled with liquid chromatography for determination of estrogen endocrine disruptors in water and human urine samples
title Development of hybrid monoliths incorporating metal–organic frameworks for stir bar sorptive extraction coupled with liquid chromatography for determination of estrogen endocrine disruptors in water and human urine samples
title_full Development of hybrid monoliths incorporating metal–organic frameworks for stir bar sorptive extraction coupled with liquid chromatography for determination of estrogen endocrine disruptors in water and human urine samples
title_fullStr Development of hybrid monoliths incorporating metal–organic frameworks for stir bar sorptive extraction coupled with liquid chromatography for determination of estrogen endocrine disruptors in water and human urine samples
title_full_unstemmed Development of hybrid monoliths incorporating metal–organic frameworks for stir bar sorptive extraction coupled with liquid chromatography for determination of estrogen endocrine disruptors in water and human urine samples
title_short Development of hybrid monoliths incorporating metal–organic frameworks for stir bar sorptive extraction coupled with liquid chromatography for determination of estrogen endocrine disruptors in water and human urine samples
title_sort development of hybrid monoliths incorporating metal–organic frameworks for stir bar sorptive extraction coupled with liquid chromatography for determination of estrogen endocrine disruptors in water and human urine samples
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821068/
https://www.ncbi.nlm.nih.gov/pubmed/35132465
http://dx.doi.org/10.1007/s00604-022-05208-6
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