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A Quantitative Systems Pharmacology Perspective on the Importance of Parameter Identifiability

There is an inherent tension in Quantitative Systems Pharmacology (QSP) between the need to incorporate mathematical descriptions of complex physiology and drug targets with the necessity of developing robust, predictive and well-constrained models. In addition to this, there is no “gold standard” f...

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Detalles Bibliográficos
Autores principales:	Sher, Anna, Niederer, Steven A., Mirams, Gary R., Kirpichnikova, Anna, Allen, Richard, Pathmanathan, Pras, Gavaghan, David J., van der Graaf, Piet H., Noble, Denis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Perspectives
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821410/ https://www.ncbi.nlm.nih.gov/pubmed/35132487 http://dx.doi.org/10.1007/s11538-021-00982-5

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