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Uncoupling protein 1 knockout aggravates isoproterenol-induced acute myocardial ischemia via AMPK/mTOR/PPARα pathways in rats

Uncoupling protein 1 (UCP1) was found exclusively in the inner membranes of the mitochondria of brown adipose tissue (BAT). We found that UCP1 was also expressed in heart tissue and significantly upregulated in isoproterenol (ISO)-induced acute myocardial ischemia (AMI) rat model. The present study...

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Detalles Bibliográficos
Autores principales:	Hou, Daorong, Fu, Heling, Zheng, Yuan, Lu, Dan, Ma, Yuanwu, Yin, Yuan, Zhang, Lianfeng, Bao, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821478/ https://www.ncbi.nlm.nih.gov/pubmed/34709566 http://dx.doi.org/10.1007/s11248-021-00289-0

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