Single-cell RNA sequencing identifies an Il1rn(+)/Trem1(+) macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissection

Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening condition characterized by medial layer degeneration of the thoracic aorta. A thorough understanding of the regulator changes during pathogenesis is essential for medical therapy development. To delineate the cellular and molecular...

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Detalles Bibliográficos
Autores principales: Liu, Xuanyu, Chen, Wen, Zhu, Guoyan, Yang, Hang, Li, Wenke, Luo, Mingyao, Shu, Chang, Zhou, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821555/
https://www.ncbi.nlm.nih.gov/pubmed/35132073
http://dx.doi.org/10.1038/s41421-021-00362-2

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