lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling

Long non-coding RNAs (lncRNAs) play critical roles in tumorigenesis and progression of colorectal cancer (CRC). However, functions of most lncRNAs in CRC and their molecular mechanisms remain uncharacterized. Here we found that lncRNA ITGB8-AS1 was highly expressed in CRC. Knockdown of ITGB8-AS1 sup...

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Detalles Bibliográficos
Autores principales: Lin, Xiaoting, Zhuang, Shiwen, Chen, Xue, Du, Jun, Zhong, Longhua, Ding, Jiancheng, Wang, Lei, Yi, Jia, Hu, Guosheng, Tang, Guohui, Luo, Xi, Liu, Wen, Ye, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821934/
https://www.ncbi.nlm.nih.gov/pubmed/34371180
http://dx.doi.org/10.1016/j.ymthe.2021.08.011

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