Bone marrow mesenchymal stem cell-derived exosomal miR-34c-5p ameliorates RIF by inhibiting the core fucosylation of multiple proteins

Renal interstitial fibrosis (RIF) is an incurable pathological lesion in chronic kidney diseases. Pericyte activation is the major pathological characteristic of RIF. Fibroblast and macrophage activation are also involved in RIF. Studies have revealed that core fucosylation (CF), an important post-t...

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Detalles Bibliográficos
Autores principales: Hu, Xuemei, Shen, Nan, Liu, Anqi, Wang, Weidong, Zhang, Lihua, Sui, Zhigang, Tang, Qingzhu, Du, Xiangning, Yang, Ning, Ying, Wantao, Qin, Biaojie, Li, Zhitong, Li, Lin, Wang, Nan, Lin, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821970/
https://www.ncbi.nlm.nih.gov/pubmed/34678513
http://dx.doi.org/10.1016/j.ymthe.2021.10.012

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