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Structural Insights Into Tautomeric Dynamics in Nucleic Acids and in Antiviral Nucleoside Analogs

DNA (2′-deoxyribonucleic acid) and RNA (ribonucleic acid) play diverse functional roles in biology and disease. Despite being comprised primarily of only four cognate nucleobases, nucleic acids can adopt complex three-dimensional structures, and RNA in particular, can catalyze biochemical reactions...

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Detalles Bibliográficos
Autores principales: Fedeles, Bogdan I., Li, Deyu, Singh, Vipender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822119/
https://www.ncbi.nlm.nih.gov/pubmed/35145998
http://dx.doi.org/10.3389/fmolb.2021.823253