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Sustained Control of Pyruvate Carboxylase by the Essential Second Messenger Cyclic di-AMP in Bacillus subtilis

In Bacillus subtilis and other Gram-positive bacteria, cyclic di-AMP is an essential second messenger that signals potassium availability by binding to a variety of proteins. In some bacteria, c-di-AMP also binds to the pyruvate carboxylase to inhibit its activity. We have discovered that in B. subt...

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Detalles Bibliográficos
Autores principales: Krüger, Larissa, Herzberg, Christina, Wicke, Dennis, Scholz, Patricia, Schmitt, Kerstin, Turdiev, Asan, Lee, Vincent T., Ischebeck, Till, Stülke, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822347/
https://www.ncbi.nlm.nih.gov/pubmed/35130724
http://dx.doi.org/10.1128/mbio.03602-21