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IS26 Veers Genomic Plasticity and Genetic Rearrangement toward Carbapenem Hyperresistance under Sublethal Antibiotics

Multidrug-resistant Gram-negative carriers of Klebsiella pneumoniae carbapenemases (KPCs) often subvert antibiotic therapy due to inadequate sensitivity in laboratory detection. Although unstable gene amplification has been recognized to crucially contribute to underestimation or misestimation of an...

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Detalles Bibliográficos
Autores principales: Wei, Da-Wei, Wong, Nai-Kei, Song, Yuqin, Zhang, Gang, Wang, Chao, Li, Juan, Feng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822349/
https://www.ncbi.nlm.nih.gov/pubmed/35130728
http://dx.doi.org/10.1128/mbio.03340-21

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