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Mismatch repair deficiency in early‐onset duodenal, ampullary, and pancreatic carcinomas is a strong indicator for a hereditary defect

Mismatch repair deficiency (dMMR) is a hallmark of Lynch syndrome (LS), but its prevalence in early‐onset (diagnosed under the age of 50 years) duodenal, ampullary, and pancreatic carcinomas (DC, AC, and PC, respectively) is largely unknown. We explored the prevalence of dMMR and the underlying mole...

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Detalles Bibliográficos
Autores principales: Kryklyva, Valentyna, Brosens, Lodewijk AA, Marijnissen‐van Zanten, Monica AJ, Ligtenberg, Marjolijn JL, Nagtegaal, Iris D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822371/
https://www.ncbi.nlm.nih.gov/pubmed/34873870
http://dx.doi.org/10.1002/cjp2.252