Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I integrity with oncocytic tumors

Papillary thyroid carcinoma tall cell variant (PTC‐TCV), a form of PTC regarded as an aggressive subtype, shares several morphologic features with oncocytic tumors. Pathogenic homoplasmic/highly heteroplasmic somatic mitochondrial DNA (mtDNA) mutations, usually affecting oxidative phosphorylation (O...

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Detalles Bibliográficos
Autores principales: Tsybrovskyy, Oleksiy, De Luise, Monica, de Biase, Dario, Caporali, Leonardo, Fiorini, Claudio, Gasparre, Giuseppe, Carelli, Valerio, Hackl, Dominik, Imamovic, Larisa, Haim, Silke, Sobrinho‐Simões, Manuel, Tallini, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822387/
https://www.ncbi.nlm.nih.gov/pubmed/34792302
http://dx.doi.org/10.1002/cjp2.247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822387/
https://www.ncbi.nlm.nih.gov/pubmed/34792302
http://dx.doi.org/10.1002/cjp2.247

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