Cargando…

Capecitabine inhibits epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells by mediating the RANK/RANKL pathway

Colorectal cancer (CRC) is the third most prevalent malignancy globally. Capecitabine is an important form of chemotherapy for colorectal cancer. The present study aims to investigate the underlying mechanism of action of the drug in CRC cells. In the present study, 50 pairs of CRC and adjacent norm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shao, Minghai, Jiang, Caiping, Yu, Changhui, Jia, Haijian, Wang, Yanli, Mao, Xinli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822391/ https://www.ncbi.nlm.nih.gov/pubmed/35154427 http://dx.doi.org/10.3892/ol.2022.13216

Ejemplares similares

CCL20 mediates RANK/RANKL-induced epithelial-mesenchymal transition in endometrial cancer cells
por: Liu, Yao, et al.
Publicado: (2016)

OCT4 Potentiates Radio-Resistance and Migration Activity of Rectal Cancer Cells by Improving Epithelial-Mesenchymal Transition in a ZEB1 Dependent Manner
por: Shao, Minghai, et al.
Publicado: (2018)

Biology of RANK, RANKL, and osteoprotegerin
por: Boyce, Brendan F, et al.
Publicado: (2007)

RANK–RANKL signalling in cancer
por: Renema, Nathalie, et al.
Publicado: (2016)

RANK/RANKL expression in prostate cancer
por: Ohtaka, Mari, et al.
Publicado: (2016)

The Roadmap of RANKL/RANK Pathway in Cancer
por: Casimiro, Sandra, et al.
Publicado: (2021)

Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines
por: Tsubaki, Masanobu, et al.
Publicado: (2013)

RANK, RANKL and osteoprotegerin in bone biology and disease
por: Wright, H. L., et al.
Publicado: (2009)

RANK/RANKL/OPG system in the intervertebral disc
por: Takegami, Norihiko, et al.
Publicado: (2017)

Circ_0000799 promotes proliferation and invasion in colorectal cancer and epithelial-mesenchymal transition
por: Geng, Chang-Hui, et al.
Publicado: (2022)

Quantitation of the Rank-Rankl Axis in Primary Biliary Cholangitis
por: Lleo, Ana, et al.
Publicado: (2016)

Targeting the RANKL/RANK/OPG Axis for Cancer Therapy
por: Ming, Jie, et al.
Publicado: (2020)

RANKL Promotes Migration and Invasion of Hepatocellular Carcinoma Cells via NF-κB-Mediated Epithelial-Mesenchymal Transition
por: Song, Fang-Nan, et al.
Publicado: (2014)

The Role of the RANKL/RANK Axis in the Prevention and Treatment of Breast Cancer with Immune Checkpoint Inhibitors and Anti-RANKL
por: Simatou, Aristofania, et al.
Publicado: (2020)

Biology of the RANKL–RANK–OPG System in Immunity, Bone, and Beyond
por: Walsh, Matthew C., et al.
Publicado: (2014)

RANK/RANKL pathway in cancer: Biological activity beyond bone?
por: Pantano, Francesco, et al.
Publicado: (2012)

RANKL/RANK: from bone loss to the prevention of breast cancer
por: Sigl, Verena, et al.
Publicado: (2016)

Dysregulation of the RANKL/RANK/OPG axis in thalassemia intermedia patients
por: Alfaqih, Mahmoud A., et al.
Publicado: (2018)

RANKL-RANK signaling regulates osteoblast differentiation and bone formation
por: Cao, Xu
Publicado: (2018)

The RANKL-RANK Axis: A Bone to Thymus Round Trip
por: Sobacchi, Cristina, et al.
Publicado: (2019)

RANK-RANKL Signaling in Cancer of the Uterine Cervix: A Review
por: van Dam, Peter A., et al.
Publicado: (2019)

Rank-Rankl-Opg Axis in Multiple Sclerosis: The Contribution of Placenta
por: Passaponti, Sofia, et al.
Publicado: (2022)

Role of Epithelial to Mesenchymal Transition in Colorectal Cancer
por: Lu, Jian, et al.
Publicado: (2023)

Retinoic Acid Increases Proliferation of Human Osteoclast Progenitors and Inhibits RANKL-Stimulated Osteoclast Differentiation by Suppressing RANK
por: Hu, Lijuan, et al.
Publicado: (2010)

FOXR2 Promotes the Proliferation, Invasion, and Epithelial–Mesenchymal Transition in Human Colorectal Cancer Cells
por: Lu, Sheng-Qiang, et al.
Publicado: (2017)

Identification of a binding site on soluble RANKL that can be targeted to inhibit soluble RANK-RANKL interactions and treat osteoporosis
por: Huang, Dane, et al.
Publicado: (2022)

NOTCH1 Mutations in Aortic Stenosis: Association with Osteoprotegerin/RANK/RANKL
por: Irtyuga, Olga, et al.
Publicado: (2017)

RANKL/RANK control Brca1 mutation-driven mammary tumors
por: Sigl, Verena, et al.
Publicado: (2016)

RANKL/RANK promotes the migration of gastric cancer cells by interacting with EGFR
por: Wan, Xing, et al.
Publicado: (2020)

Association of Polymorphisms in RANK and RANKL Genes with Osteopenia in Arab Postmenopausal Women
por: Abdi, Saba, et al.
Publicado: (2020)

RANK/RANKL/OPG Signaling in the Brain: A Systematic Review of the Literature
por: Glasnović, Anton, et al.
Publicado: (2020)

RANKL and RANK in extracellular vesicles: surprising new players in bone remodeling
por: Holliday, L. Shannon, et al.
Publicado: (2021)

Soy Isoflavones and Bone Health: Focus on the RANKL/RANK/OPG Pathway
por: Hooshiar, Saeedeh Hosseini, et al.
Publicado: (2022)

Mesenchymal stem cells inhibit RANK-RANKL interactions between osteoclasts and Th17 cells via osteoprotegerin activity
por: Cho, Kyung-Ah, et al.
Publicado: (2017)

Disturbance of the OPG/RANK/RANKL pathway and systemic inflammation in COPD patients with emphysema and osteoporosis
por: Bai, Peng, et al.
Publicado: (2011)

CircLMNB1 promotes colorectal cancer by regulating cell proliferation, apoptosis and epithelial-mesenchymal transition
por: He, Chunping, et al.
Publicado: (2019)

Baicalein suppresses the proliferation and invasiveness of colorectal cancer cells by inhibiting Snail-induced epithelial-mesenchymal transition
por: Zeng, Qiongyao, et al.
Publicado: (2020)

RANK/RANKL/OPG Signalization Implication in Periodontitis: New Evidence from a RANK Transgenic Mouse Model
por: Sojod, Bouchra, et al.
Publicado: (2017)

RBP2 Induces Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer
por: Wang, Shikun, et al.
Publicado: (2013)

Curcumin Inhibits Proliferation and Epithelial-Mesenchymal Transition in Lens Epithelial Cells through Multiple Pathways
por: Liu, Huijun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m3h6fmprn1fg6ln103n7vbumnu