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Relationship of cytochrome P450 gene polymorphisms with blood concentrations of hydroxychloroquine and its metabolites and adverse drug reactions

BACKGROUND: Hydroxychloroquine (HCQ) is a cornerstone therapy for systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). This study aimed to investigate the relationship of cytochrome P450 (CYP450) gene polymorphisms with blood concentrations of HCQ and its metabolites and adverse drug re...

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Detalles Bibliográficos
Autores principales:	Gao, Beibei, Tan, Tingfei, Cao, Xi, Pan, Menglu, Yang, Chunlan, Wang, Jianxiong, Shuai, Zongwen, Xia, Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822703/ https://www.ncbi.nlm.nih.gov/pubmed/35135554 http://dx.doi.org/10.1186/s12920-022-01171-6

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