Cargando…

Marine fungal metabolite butyrolactone I prevents cognitive deficits by relieving inflammation and intestinal microbiota imbalance on aluminum trichloride-injured zebrafish

BACKGROUND: Mounting evidences indicate that oxidative stress, neuroinflammation, and dysregulation of gut microbiota are related to neurodegenerative disorders (NDs). Butyrolactone I (BTL-I), a marine fungal metabolite, was previously reported as an in vitro neuroprotectant and inflammation inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales: Nie, Yingying, Yang, Jingming, Zhou, Longjian, Yang, Zhiyou, Liang, Jinyue, Liu, Yayue, Ma, Xiaoxiang, Qian, Zhongji, Hong, Pengzhi, Kalueff, Allan V., Song, Cai, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822793/
https://www.ncbi.nlm.nih.gov/pubmed/35130930
http://dx.doi.org/10.1186/s12974-022-02403-3