Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1

BACKGROUND: Inhalation of dust containing silica particles is associated with severe pulmonary inflammation and lung injury leading to chronic silicosis including fibrotic remodeling of the lung. Silicosis represents a major global health problem causing more than 45.000 deaths per year. The inflamm...

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Detalles Bibliográficos
Autores principales: Peukert, Konrad, Steinhagen, Folkert, Fox, Mario, Feuerborn, Caroline, Schulz, Susanne, Seeliger, Benjamin, Schuss, Patrick, Schneider, Matthias, Frede, Stilla, Sauer, Andrea, Putensen, Christian, Latz, Eicke, Wilhelm, Christoph, Bode, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822850/
https://www.ncbi.nlm.nih.gov/pubmed/35130879
http://dx.doi.org/10.1186/s12931-022-01937-7

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