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A role for the NPM1/PTPN14/YAP axis in mediating hypoxia-induced chemoresistance to sorafenib in hepatocellular carcinoma

BACKGROUND: Tumor microenvironments are characterized by resistance to chemotherapeutic agents and radiotherapy. Hypoxia plays an important role in the development of tumor resistance, as well as the generation of metastatic potential. YAP also participates in the regulation of hypoxia-mediated chem...

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Detalles Bibliográficos
Autores principales:	Zhang, Dengke, Wu, Fazong, Song, Jingjing, Meng, Miaomiao, Fan, Xiaoxi, Lu, Chenying, Weng, Qiaoyou, Fang, Shiji, Zheng, Liyun, Tang, Bufu, Yang, Yang, Tu, Jianfei, Xu, Min, Zhao, Zhongwei, Ji, Jiansong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822852/ https://www.ncbi.nlm.nih.gov/pubmed/35135548 http://dx.doi.org/10.1186/s12935-022-02479-0

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