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4329 Investigating the role of Klotho in neurocognitive outcomes, brain volumes, and white matter changes in pediatric brain tumor survivors

OBJECTIVES/GOALS: Klotho is a protein linked to improved cognition in aging adults. A specific KLOTHO gene variant, KL-VS, increases circulating levels of Klotho. The current study aims to identify if the KL-VS haplotype and Klotho levels are associated with improved neurocognition in pediatric brai...

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Detalles Bibliográficos
Autores principales:	Edwards, Caleb Simpeh, Stoller, Schuyler, Savchuk, Sol, Ugaz Valencia, Christian Rodrigo, Tong, Liz, Rauschecker, Andreas, Dubal, Dena, Kline, Cassie, Mueller, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2020
Materias:	Mechanistic Basic to Clinical
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822916/ http://dx.doi.org/10.1017/cts.2020.305

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