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4547 Understanding the molecular mechanism of natural killer cell deficiency to improve natural killer cell in vitro differentiation for therapeutics

OBJECTIVES/GOALS: Natural killer (NK) cells are a potential cancer therapeutic but expanding NK cells efficiently in vitro is difficult. Natural killer cell deficiency (NKD), a primary immune deficiency affecting only NK cells, is caused by defects in several DNA replication proteins. By studying NK...

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Detalles Bibliográficos
Autores principales:	Schmit, Megan, Baxley, Ryan, Mace, Emily, Orange, Jordan, Miller, Jeffery, Bielinsky, Anja-Katrin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2020
Materias:	Basic Science/Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823218/ http://dx.doi.org/10.1017/cts.2020.101

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