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4573 Characterization of vascular disease in an Acta2 mutant mouse model

OBJECTIVES/GOALS: ACTA2 R179 carriers present with early-onset stroke; occlusive lesions of the distal internal carotid artery and branches are filled with cells staining positive for smooth muscle cell (SMC) markers. We will identify pathways leading to increased SMC proliferation and migration and...

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Detalles Bibliográficos
Autores principales:	Kaw, Anita, Kwartler, Callie, Chattopadhyay, Abhijnan, Milewicz, Dianna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2020
Materias:	Translational Science, Policy, & Health Outcomes Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823325/ http://dx.doi.org/10.1017/cts.2020.375

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