4336 Renal Tubular Complement C9 Deposition is Associated with Renal Tubular Damage and Fibrosis in Lupus Nephritis

OBJECTIVES/GOALS: Tubulointerstitial damage in lupus nephritis (LN) is a strong predictor of progression to chronic kidney disease and end stage renal disease (ESRD). While complement activation mediates glomerular injury, the role of complement in renal tubular damage has not been evaluated. We inv...

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Detalles Bibliográficos
Autores principales: Wang, Shudan, Wu, Ming, Chiriboga, Luis, Putterman, Chaim, Broder, Anna, Belmont, H. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Translational Science, Policy, & Health Outcomes Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823412/
http://dx.doi.org/10.1017/cts.2020.424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823412/
http://dx.doi.org/10.1017/cts.2020.424

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