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4308 DEEP-PRIMED IL-15 SUPERAGONIST IMPROVES ANTIVIRAL EFFICACY OF HIV-SPECIFIC CD8(+) T-CELLS IN HUMANIZED MOUSE MODEL

OBJECTIVES/GOALS: HIV-specific CD8(+) T-cells play a critical role in partially controlling viral replication in infected-individuals, but ultimately fail to eliminate infection. Enhancing these T-cell responses through lymphocyte engineering approaches has the potential as a novel therapy capable o...

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Detalles Bibliográficos
Autores principales:	McCann, Chase Daniel, Zale, Elizabeth, Ward, Adam, Dilling, Thomas, Danesh, Ali, Stevenson, Eva, Mota, Talia, Boesch, Austin, Andresen, Thomas, Irvine, Darrell, Jones, R. Brad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2020
Materias:	Basic Science/Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823420/ http://dx.doi.org/10.1017/cts.2020.59

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