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4168 Understanding ECM-Based Drug Resistivity in Breast Cancer

OBJECTIVES/GOALS: Cell-cell (CC) and cell-matrix interactions (CM) are known to affect drug sensitivity of cancer cells, but are not effectively recapitulated using 2D platforms. This research aims to determine how cell and matrix interactions confer drug resistivity in 3 distinct culturing models:...

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Detalles Bibliográficos
Autores principales:	Libring, Sarah, Shinde, Aparna, Boodaghidizaji, Miad, Plummer, Alexandra, Ardekani, Arezoo, Wendt, Michael, Solorio, Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2020
Materias:	Precision Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823421/ http://dx.doi.org/10.1017/cts.2020.346

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