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4353 The Role of BCL2 Mediated Calcium Signaling on Leukemia Stem Cell Metabolism

OBJECTIVES/GOALS: The objective of this study is to define the molecular mechanisms that control survival of malignant stem cells in acute myeloid leukemia (AML). Leukemia stem cells (LSCs) are not effectively eradicated by standard treatment and lead to resistance and relapse, which contribute to p...

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Detalles Bibliográficos
Autores principales:	Inguva, Anagha, Pei, Shanshan, Amaya, Maria, Stevens, Brett, Jones, Courtney, Pollyea, Daniel, Jordan, Craig
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2020
Materias:	Basic Science/Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823647/ http://dx.doi.org/10.1017/cts.2020.98

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