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4094 Structural Determinants of Immunogenicity for Peptide-Based Immunotherapy

OBJECTIVES/GOALS: Neoantigen vaccine immunotherapies have shown promise in clinical trials, but identifying which peptides to include in a vaccine remains a challenge. We aim to establish that molecular structural features can help predict which neoantigens to target to achieve tumor regression. MET...

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Detalles Bibliográficos
Autores principales: Devlin, Jason, Alonso, Jesus, Keller, Grant, Bobisse, Sara, Harari, Alexandre, Baker, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823648/
http://dx.doi.org/10.1017/cts.2020.92

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