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Mapping the invisible chromatin transactions of prophase chromosome remodeling

We have used a combination of chemical genetics, chromatin proteomics, and imaging to map the earliest chromatin transactions during vertebrate cell entry into mitosis. Chicken DT40 CDK1(as) cells undergo synchronous mitotic entry within 15 min following release from a 1NM-PP1-induced arrest in late...

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Detalles Bibliográficos
Autores principales: Samejima, Itaru, Spanos, Christos, Samejima, Kumiko, Rappsilber, Juri, Kustatscher, Georg, Earnshaw, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823707/
https://www.ncbi.nlm.nih.gov/pubmed/35090599
http://dx.doi.org/10.1016/j.molcel.2021.12.039