Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering

It is unclear whether SARS-CoV-2 VOCs differentially escape Fc effector functions of antibodies in addition to neutralization. In this issue of Cell Reports Medicine, Richardson et al.(1) show that VOCs differ both in their ability to evade as well as elicit cross-reactive Fc-effector functions.

Detalles Bibliográficos
Autores principales: Grunst, Michael W., Uchil, Pradeep D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Preview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823971/
https://www.ncbi.nlm.nih.gov/pubmed/35233551
http://dx.doi.org/10.1016/j.xcrm.2022.100540
Descripción
Sumario:It is unclear whether SARS-CoV-2 VOCs differentially escape Fc effector functions of antibodies in addition to neutralization. In this issue of Cell Reports Medicine, Richardson et al.(1) show that VOCs differ both in their ability to evade as well as elicit cross-reactive Fc-effector functions.

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