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Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering
It is unclear whether SARS-CoV-2 VOCs differentially escape Fc effector functions of antibodies in addition to neutralization. In this issue of Cell Reports Medicine, Richardson et al.(1) show that VOCs differ both in their ability to evade as well as elicit cross-reactive Fc-effector functions.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823971/ https://www.ncbi.nlm.nih.gov/pubmed/35233551 http://dx.doi.org/10.1016/j.xcrm.2022.100540 |
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author | Grunst, Michael W. Uchil, Pradeep D. |
author_facet | Grunst, Michael W. Uchil, Pradeep D. |
author_sort | Grunst, Michael W. |
collection | PubMed |
description | It is unclear whether SARS-CoV-2 VOCs differentially escape Fc effector functions of antibodies in addition to neutralization. In this issue of Cell Reports Medicine, Richardson et al.(1) show that VOCs differ both in their ability to evade as well as elicit cross-reactive Fc-effector functions. |
format | Online Article Text |
id | pubmed-8823971 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-88239712022-02-09 Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering Grunst, Michael W. Uchil, Pradeep D. Cell Rep Med Preview It is unclear whether SARS-CoV-2 VOCs differentially escape Fc effector functions of antibodies in addition to neutralization. In this issue of Cell Reports Medicine, Richardson et al.(1) show that VOCs differ both in their ability to evade as well as elicit cross-reactive Fc-effector functions. Elsevier 2022-02-08 /pmc/articles/PMC8823971/ /pubmed/35233551 http://dx.doi.org/10.1016/j.xcrm.2022.100540 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Preview Grunst, Michael W. Uchil, Pradeep D. Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering |
title | Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering |
title_full | Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering |
title_fullStr | Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering |
title_full_unstemmed | Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering |
title_short | Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering |
title_sort | fc effector cross-reactivity: a hidden arsenal against sars-cov-2’s evasive maneuvering |
topic | Preview |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823971/ https://www.ncbi.nlm.nih.gov/pubmed/35233551 http://dx.doi.org/10.1016/j.xcrm.2022.100540 |
work_keys_str_mv | AT grunstmichaelw fceffectorcrossreactivityahiddenarsenalagainstsarscov2sevasivemaneuvering AT uchilpradeepd fceffectorcrossreactivityahiddenarsenalagainstsarscov2sevasivemaneuvering |