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Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering

It is unclear whether SARS-CoV-2 VOCs differentially escape Fc effector functions of antibodies in addition to neutralization. In this issue of Cell Reports Medicine, Richardson et al.(1) show that VOCs differ both in their ability to evade as well as elicit cross-reactive Fc-effector functions.

Detalles Bibliográficos
Autores principales: Grunst, Michael W., Uchil, Pradeep D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823971/
https://www.ncbi.nlm.nih.gov/pubmed/35233551
http://dx.doi.org/10.1016/j.xcrm.2022.100540
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author Grunst, Michael W.
Uchil, Pradeep D.
author_facet Grunst, Michael W.
Uchil, Pradeep D.
author_sort Grunst, Michael W.
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description It is unclear whether SARS-CoV-2 VOCs differentially escape Fc effector functions of antibodies in addition to neutralization. In this issue of Cell Reports Medicine, Richardson et al.(1) show that VOCs differ both in their ability to evade as well as elicit cross-reactive Fc-effector functions.
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spelling pubmed-88239712022-02-09 Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering Grunst, Michael W. Uchil, Pradeep D. Cell Rep Med Preview It is unclear whether SARS-CoV-2 VOCs differentially escape Fc effector functions of antibodies in addition to neutralization. In this issue of Cell Reports Medicine, Richardson et al.(1) show that VOCs differ both in their ability to evade as well as elicit cross-reactive Fc-effector functions. Elsevier 2022-02-08 /pmc/articles/PMC8823971/ /pubmed/35233551 http://dx.doi.org/10.1016/j.xcrm.2022.100540 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Preview
Grunst, Michael W.
Uchil, Pradeep D.
Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering
title Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering
title_full Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering
title_fullStr Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering
title_full_unstemmed Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering
title_short Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2’s evasive maneuvering
title_sort fc effector cross-reactivity: a hidden arsenal against sars-cov-2’s evasive maneuvering
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8823971/
https://www.ncbi.nlm.nih.gov/pubmed/35233551
http://dx.doi.org/10.1016/j.xcrm.2022.100540
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