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TDRD3 is an antiviral restriction factor that promotes IFN signaling with G3BP1

Stress granules (SGs) are highly dynamic cytoplasmic foci that form in response to activation of the integrated stress response (ISR) that results in eIF2α phosphorylation and global translation shutdown. Stress granules, which are largely nucleated by G3BP1, serve as hubs for mRNA triage, but there...

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Detalles Bibliográficos
Autores principales: Deater, Matthew, Tamhankar, Manasi, Lloyd, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824378/
https://www.ncbi.nlm.nih.gov/pubmed/35085371
http://dx.doi.org/10.1371/journal.ppat.1010249