Cargando…

Pre-tibial myopericytoma: a case report

Myopericytoma (MPC) is a rare, benign tumour often presenting as a cutaneous growth commonly in the lower extremities. It is distinguished by its concentric layering of spindle shaped myoid appearing cells perivascularly. These cells diagnostically stain positive to alpha smooth-muscle actin and rar...

Descripción completa

Detalles Bibliográficos
Autores principales: Cockburn, Claudia J K, Crene, Elliot J D, Cockburn, William J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824466/
https://www.ncbi.nlm.nih.gov/pubmed/35145630
http://dx.doi.org/10.1093/jscr/rjac021
_version_ 1784647022715863040
author Cockburn, Claudia J K
Crene, Elliot J D
Cockburn, William J
author_facet Cockburn, Claudia J K
Crene, Elliot J D
Cockburn, William J
author_sort Cockburn, Claudia J K
collection PubMed
description Myopericytoma (MPC) is a rare, benign tumour often presenting as a cutaneous growth commonly in the lower extremities. It is distinguished by its concentric layering of spindle shaped myoid appearing cells perivascularly. These cells diagnostically stain positive to alpha smooth-muscle actin and rarely positive to desmin stain. This case study reviews the presentation of a 56-year-old male with a slow-growing, pre-tibial lesion developing over a 7–8 year period. This lesion was asymptomatic and demonstrated vascular involvement on ultrasound scan. This lesion measured 19 × 15 × 9 mm histologically and contained bland spindle cells surrounding vessels that interestingly stained positive to both alpha smooth-muscle actin and desmin. The histological findings in correlation to clinical presentation and imaging led to a diagnosis of MPC.
format Online
Article
Text
id pubmed-8824466
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-88244662022-02-09 Pre-tibial myopericytoma: a case report Cockburn, Claudia J K Crene, Elliot J D Cockburn, William J J Surg Case Rep Case Report Myopericytoma (MPC) is a rare, benign tumour often presenting as a cutaneous growth commonly in the lower extremities. It is distinguished by its concentric layering of spindle shaped myoid appearing cells perivascularly. These cells diagnostically stain positive to alpha smooth-muscle actin and rarely positive to desmin stain. This case study reviews the presentation of a 56-year-old male with a slow-growing, pre-tibial lesion developing over a 7–8 year period. This lesion was asymptomatic and demonstrated vascular involvement on ultrasound scan. This lesion measured 19 × 15 × 9 mm histologically and contained bland spindle cells surrounding vessels that interestingly stained positive to both alpha smooth-muscle actin and desmin. The histological findings in correlation to clinical presentation and imaging led to a diagnosis of MPC. Oxford University Press 2022-02-02 /pmc/articles/PMC8824466/ /pubmed/35145630 http://dx.doi.org/10.1093/jscr/rjac021 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cockburn, Claudia J K
Crene, Elliot J D
Cockburn, William J
Pre-tibial myopericytoma: a case report
title Pre-tibial myopericytoma: a case report
title_full Pre-tibial myopericytoma: a case report
title_fullStr Pre-tibial myopericytoma: a case report
title_full_unstemmed Pre-tibial myopericytoma: a case report
title_short Pre-tibial myopericytoma: a case report
title_sort pre-tibial myopericytoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824466/
https://www.ncbi.nlm.nih.gov/pubmed/35145630
http://dx.doi.org/10.1093/jscr/rjac021
work_keys_str_mv AT cockburnclaudiajk pretibialmyopericytomaacasereport
AT creneelliotjd pretibialmyopericytomaacasereport
AT cockburnwilliamj pretibialmyopericytomaacasereport