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Pre-tibial myopericytoma: a case report
Myopericytoma (MPC) is a rare, benign tumour often presenting as a cutaneous growth commonly in the lower extremities. It is distinguished by its concentric layering of spindle shaped myoid appearing cells perivascularly. These cells diagnostically stain positive to alpha smooth-muscle actin and rar...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824466/ https://www.ncbi.nlm.nih.gov/pubmed/35145630 http://dx.doi.org/10.1093/jscr/rjac021 |
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author | Cockburn, Claudia J K Crene, Elliot J D Cockburn, William J |
author_facet | Cockburn, Claudia J K Crene, Elliot J D Cockburn, William J |
author_sort | Cockburn, Claudia J K |
collection | PubMed |
description | Myopericytoma (MPC) is a rare, benign tumour often presenting as a cutaneous growth commonly in the lower extremities. It is distinguished by its concentric layering of spindle shaped myoid appearing cells perivascularly. These cells diagnostically stain positive to alpha smooth-muscle actin and rarely positive to desmin stain. This case study reviews the presentation of a 56-year-old male with a slow-growing, pre-tibial lesion developing over a 7–8 year period. This lesion was asymptomatic and demonstrated vascular involvement on ultrasound scan. This lesion measured 19 × 15 × 9 mm histologically and contained bland spindle cells surrounding vessels that interestingly stained positive to both alpha smooth-muscle actin and desmin. The histological findings in correlation to clinical presentation and imaging led to a diagnosis of MPC. |
format | Online Article Text |
id | pubmed-8824466 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-88244662022-02-09 Pre-tibial myopericytoma: a case report Cockburn, Claudia J K Crene, Elliot J D Cockburn, William J J Surg Case Rep Case Report Myopericytoma (MPC) is a rare, benign tumour often presenting as a cutaneous growth commonly in the lower extremities. It is distinguished by its concentric layering of spindle shaped myoid appearing cells perivascularly. These cells diagnostically stain positive to alpha smooth-muscle actin and rarely positive to desmin stain. This case study reviews the presentation of a 56-year-old male with a slow-growing, pre-tibial lesion developing over a 7–8 year period. This lesion was asymptomatic and demonstrated vascular involvement on ultrasound scan. This lesion measured 19 × 15 × 9 mm histologically and contained bland spindle cells surrounding vessels that interestingly stained positive to both alpha smooth-muscle actin and desmin. The histological findings in correlation to clinical presentation and imaging led to a diagnosis of MPC. Oxford University Press 2022-02-02 /pmc/articles/PMC8824466/ /pubmed/35145630 http://dx.doi.org/10.1093/jscr/rjac021 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2022. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Cockburn, Claudia J K Crene, Elliot J D Cockburn, William J Pre-tibial myopericytoma: a case report |
title | Pre-tibial myopericytoma: a case report |
title_full | Pre-tibial myopericytoma: a case report |
title_fullStr | Pre-tibial myopericytoma: a case report |
title_full_unstemmed | Pre-tibial myopericytoma: a case report |
title_short | Pre-tibial myopericytoma: a case report |
title_sort | pre-tibial myopericytoma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824466/ https://www.ncbi.nlm.nih.gov/pubmed/35145630 http://dx.doi.org/10.1093/jscr/rjac021 |
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