Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon hepatitis B vaccination

Antigen recognition through the T cell receptor (TCR) αβ heterodimer is one of the primary determinants of the adaptive immune response. Vaccines activate naïve T cells with high specificity to expand and differentiate into memory T cells. However, antigen-specific memory CD4 T cells exist in unexpo...

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Detalles Bibliográficos
Autores principales: Elias, George, Meysman, Pieter, Bartholomeus, Esther, De Neuter, Nicolas, Keersmaekers, Nina, Suls, Arvid, Jansens, Hilde, Souquette, Aisha, De Reu, Hans, Emonds, Marie-Paule, Smits, Evelien, Lion, Eva, Thomas, Paul G, Mortier, Geert, Van Damme, Pierre, Beutels, Philippe, Laukens, Kris, Van Tendeloo, Viggo, Ogunjimi, Benson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824481/
https://www.ncbi.nlm.nih.gov/pubmed/35074048
http://dx.doi.org/10.7554/eLife.68388

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