Small Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhanced Proangiogenic Potential of Cardiac Fibroblasts via Angiopoietin-Like 4

METHODS AND RESULTS: We isolated primary CFs from Sprague-Dawley rats (1–3 days old) and treated them with lipopolysaccharide (LPS) and LPS+sEVs. RNA sequencing analysis revealed that angiopoietin-like 4 (Angptl4) was increased in the LPS+sEVs group more than in the LPS group. After inhibition of An...

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Detalles Bibliográficos
Autores principales: Li, Jiejie, Xu, Xin, Fei, Suyan, Wang, Ren, Wang, Hua, Zhu, Wei, Zhao, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824744/
https://www.ncbi.nlm.nih.gov/pubmed/35154329
http://dx.doi.org/10.1155/2022/3229289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824744/
https://www.ncbi.nlm.nih.gov/pubmed/35154329
http://dx.doi.org/10.1155/2022/3229289

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