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Small Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhanced Proangiogenic Potential of Cardiac Fibroblasts via Angiopoietin-Like 4

METHODS AND RESULTS: We isolated primary CFs from Sprague-Dawley rats (1–3 days old) and treated them with lipopolysaccharide (LPS) and LPS+sEVs. RNA sequencing analysis revealed that angiopoietin-like 4 (Angptl4) was increased in the LPS+sEVs group more than in the LPS group. After inhibition of An...

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Detalles Bibliográficos
Autores principales:	Li, Jiejie, Xu, Xin, Fei, Suyan, Wang, Ren, Wang, Hua, Zhu, Wei, Zhao, Yuanyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824744/ https://www.ncbi.nlm.nih.gov/pubmed/35154329 http://dx.doi.org/10.1155/2022/3229289

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