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Galectin-1-Dependent Mitochondria Apoptosis Plays an Essential Role in the Potential Protein Targets of DBDCT-Induced Hepatotoxicity as Revealed by Quantitative Proteomic Analyses

Di-n-butyl-di-(4-chlorobenzohydroxamato) tin(IV) (DBDCT), a new patent agent, exhibited strong antitumor activity. In some cases, its activity was close to or even higher than cisplatin, a first-line clinical metallic agent. Similar to platinum compounds, it also showed toxicity. However, the effect...

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Detalles Bibliográficos
Autores principales: Song, Jiayu, Ren, Yuan, Liu, Lihua, Wang, Yixin, Shi, Chuandao, Ji, Xiaoqing, Li, Yunlan, Li, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824758/
https://www.ncbi.nlm.nih.gov/pubmed/35154294
http://dx.doi.org/10.1155/2022/5176300