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A Targeted Complement Inhibitor CRIg/FH Protects Against Experimental Autoimmune Myasthenia Gravis in Rats via Immune Modulation
Antibody-induced complement activation may cause injury of the neuromuscular junction (NMJ) and is thus considered as a primary pathogenic factor in human myasthenia gravis (MG) and animal models of experimental autoimmune myasthenia gravis (EAMG). In this study, we tested whether CRIg/FH, a targete...
Autores principales: | Song, Jie, Zhao, Rui, Yan, Chong, Luo, Sushan, Xi, Jianying, Ding, Peipei, Li, Ling, Hu, Weiguo, Zhao, Chongbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825366/ https://www.ncbi.nlm.nih.gov/pubmed/35154091 http://dx.doi.org/10.3389/fimmu.2022.746068 |
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