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SRSF1 Deficiency Impairs the Late Thymocyte Maturation and the CD8 Single-Positive Lineage Fate Decision

The underlying mechanisms of thymocyte development and lineage determination remain incompletely understood, and the emerging evidences demonstrated that RNA binding proteins (RBPs) are deeply involved in governing T cell fate in thymus. Serine/arginine-rich splicing factor 1 (SRSF1), as a classical...

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Detalles Bibliográficos
Autores principales: Ji, Ce, Bao, Li, Yuan, Shunzong, Qi, Zhihong, Wang, Fang, You, Menghao, Yu, Guotao, Liu, Jingjing, Cui, Xiao, Wang, Zhao, Liu, Juanjuan, Guo, Wenhui, Feng, Mingxia, Chen, Feng, Kang, Youmin, Yu, Shuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825371/
https://www.ncbi.nlm.nih.gov/pubmed/35154164
http://dx.doi.org/10.3389/fimmu.2022.838719