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Oxysterols Protect Epithelial Cells Against Pore-Forming Toxins
Many species of bacteria produce toxins such as cholesterol-dependent cytolysins that form pores in cell membranes. Membrane pores facilitate infection by releasing nutrients, delivering virulence factors, and causing lytic cell damage - cytolysis. Oxysterols are oxidized forms of cholesterol that r...
Autores principales: | Ormsby, Thomas J. R., Owens, Sian E., Clement, Liam, Mills, Tom J., Cronin, James G., Bromfield, John J., Sheldon, Iain Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825411/ https://www.ncbi.nlm.nih.gov/pubmed/35154132 http://dx.doi.org/10.3389/fimmu.2022.815775 |
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