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Oxysterols Protect Epithelial Cells Against Pore-Forming Toxins

Many species of bacteria produce toxins such as cholesterol-dependent cytolysins that form pores in cell membranes. Membrane pores facilitate infection by releasing nutrients, delivering virulence factors, and causing lytic cell damage - cytolysis. Oxysterols are oxidized forms of cholesterol that r...

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Detalles Bibliográficos
Autores principales: Ormsby, Thomas J. R., Owens, Sian E., Clement, Liam, Mills, Tom J., Cronin, James G., Bromfield, John J., Sheldon, Iain Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825411/
https://www.ncbi.nlm.nih.gov/pubmed/35154132
http://dx.doi.org/10.3389/fimmu.2022.815775

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