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Research Progress of UiO-66-Based Electrochemical Biosensors

UiO-66, as a member of the MOFs families, is widely employed in sensing, drug release, separation, and adsorption due to its large specific surface area, uniform pore size, easy functionalization, and excellent stability. Especially in electrochemical biosensors, UiO-66 has demonstrated excellent ad...

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Autores principales: Wu, Ming, Zhang, Qi, Zhang, Qiuyu, Wang, Huan, Wang, Fawei, Liu, Junmei, Guo, Liquan, Song, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825417/
https://www.ncbi.nlm.nih.gov/pubmed/35155373
http://dx.doi.org/10.3389/fchem.2022.842894
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author Wu, Ming
Zhang, Qi
Zhang, Qiuyu
Wang, Huan
Wang, Fawei
Liu, Junmei
Guo, Liquan
Song, Kai
author_facet Wu, Ming
Zhang, Qi
Zhang, Qiuyu
Wang, Huan
Wang, Fawei
Liu, Junmei
Guo, Liquan
Song, Kai
author_sort Wu, Ming
collection PubMed
description UiO-66, as a member of the MOFs families, is widely employed in sensing, drug release, separation, and adsorption due to its large specific surface area, uniform pore size, easy functionalization, and excellent stability. Especially in electrochemical biosensors, UiO-66 has demonstrated excellent adsorption capacity and response signal, which significantly improves the sensitivity and specificity of detection. However, the existing application research remains in its infancy, lacking systematic methods, and recycling utilization and exclusive sensing of UiO-66 still require further improvement. Therefore, one of the present research objectives is to explore the breakthrough point of existing technologies and optimize the performance of UiO-66-based electrochemical biosensors (UiO-66-EBs). In this work, we summarized current experimental methods and detection mechanisms of UiO-66-EBs in environmental detection, food safety, and disease diagnosis, analyzed the existing problems, and proposed some suggestions to provide new ideas for future research.
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spelling pubmed-88254172022-02-10 Research Progress of UiO-66-Based Electrochemical Biosensors Wu, Ming Zhang, Qi Zhang, Qiuyu Wang, Huan Wang, Fawei Liu, Junmei Guo, Liquan Song, Kai Front Chem Chemistry UiO-66, as a member of the MOFs families, is widely employed in sensing, drug release, separation, and adsorption due to its large specific surface area, uniform pore size, easy functionalization, and excellent stability. Especially in electrochemical biosensors, UiO-66 has demonstrated excellent adsorption capacity and response signal, which significantly improves the sensitivity and specificity of detection. However, the existing application research remains in its infancy, lacking systematic methods, and recycling utilization and exclusive sensing of UiO-66 still require further improvement. Therefore, one of the present research objectives is to explore the breakthrough point of existing technologies and optimize the performance of UiO-66-based electrochemical biosensors (UiO-66-EBs). In this work, we summarized current experimental methods and detection mechanisms of UiO-66-EBs in environmental detection, food safety, and disease diagnosis, analyzed the existing problems, and proposed some suggestions to provide new ideas for future research. Frontiers Media S.A. 2022-01-26 /pmc/articles/PMC8825417/ /pubmed/35155373 http://dx.doi.org/10.3389/fchem.2022.842894 Text en Copyright © 2022 Wu, Zhang, Zhang, Wang, Wang, Liu, Guo and Song. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Wu, Ming
Zhang, Qi
Zhang, Qiuyu
Wang, Huan
Wang, Fawei
Liu, Junmei
Guo, Liquan
Song, Kai
Research Progress of UiO-66-Based Electrochemical Biosensors
title Research Progress of UiO-66-Based Electrochemical Biosensors
title_full Research Progress of UiO-66-Based Electrochemical Biosensors
title_fullStr Research Progress of UiO-66-Based Electrochemical Biosensors
title_full_unstemmed Research Progress of UiO-66-Based Electrochemical Biosensors
title_short Research Progress of UiO-66-Based Electrochemical Biosensors
title_sort research progress of uio-66-based electrochemical biosensors
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825417/
https://www.ncbi.nlm.nih.gov/pubmed/35155373
http://dx.doi.org/10.3389/fchem.2022.842894
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