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An Emerging Role of TIM3 Expression on T Cells in Chronic Kidney Inflammation

T cell immunoglobulin domain and mucin domain 3 (TIM3) was initially identified as an inhibitory molecule on IFNγ-producing T cells. Further research discovered the broad expression of TIM3 on different immune cells binding to multiple ligands. Apart from its suppressive effects on the Th1 cells, re...

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Detalles Bibliográficos
Autores principales: Lu, Can, Chen, Huihui, Wang, Chang, Yang, Fei, Li, Jun, Liu, Hong, Chen, Guochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825483/
https://www.ncbi.nlm.nih.gov/pubmed/35154075
http://dx.doi.org/10.3389/fimmu.2021.798683