Cargando…

The decreased expression of miR-429 in plasma exosomes after spinal cord injury inhibits neuronal apoptosis by mediating the PTEN/PI3K/Akt pathway

BACKGROUND: Neuronal apoptosis after spinal cord injury (SCI) leads to sensorial and motorial dysfunction. Exosomes are vesicles that contain many cellular components, including microRNA, and the role of miR-429 in plasma exosomes in this process after SCI requires further investigation. METHODS: Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Jiayi, Wu, Chunshuai, Xu, Guanhua, Sun, Yue, Gui, Chao, Fu, Jiawei, Cui, Zhiming, Huang, Haiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825548/ https://www.ncbi.nlm.nih.gov/pubmed/35242851 http://dx.doi.org/10.21037/atm-21-5561

Ejemplares similares

Bioinformatic Analysis of the Proteome in Exosomes Derived From Plasma: Exosomes Involved in Cholesterol Metabolism Process of Patients With Spinal Cord Injury in the Acute Phase
por: Wu, Chunshuai, et al.
Publicado: (2021)

The pathogenesis of DLD-mediated cuproptosis induced spinal cord injury and its regulation on immune microenvironment
por: Li, Chaochen, et al.
Publicado: (2023)

CCR7-mediated T follicular helper cell differentiation is associated with the pathogenesis and immune microenvironment of spinal cord injury-induced immune deficiency syndrome
por: Li, Chaochen, et al.
Publicado: (2022)

Effect of miR-106b on Invasiveness of Pituitary Adenoma via PTEN-PI3K/AKT
por: Zheng, Zhiming, et al.
Publicado: (2017)

Exosomes derived from miR-26a-modified MSCs promote axonal regeneration via the PTEN/AKT/mTOR pathway following spinal cord injury
por: Chen, Yuyong, et al.
Publicado: (2021)

Circulating exosomal miR-21 mediates HUVEC proliferation and migration through PTEN/PI3K/AKT in Crohn’s disease
por: Xie, Xiaoran, et al.
Publicado: (2022)

Exosomes Derived from Nerve Stem Cells Loaded with FTY720 Promote the Recovery after Spinal Cord Injury in Rats by PTEN/AKT Signal Pathway
por: Chen, Jianbin, et al.
Publicado: (2021)

Formaldehyde induces the apoptosis of BMCs of BALB/c mice via the PTEN/PI3K/Akt signal transduction pathway
por: Yu, Guangyan, et al.
Publicado: (2019)

MiR‐19b‐3p accelerates bone loss after spinal cord injury by suppressing osteogenesis via regulating PTEN/Akt/mTOR signalling
por: Liu, Da, et al.
Publicado: (2020)

EPDR1, Which Is Negatively Regulated by miR-429, Suppresses Epithelial Ovarian Cancer Progression via PI3K/AKT Signaling Pathway
por: Zhao, Zhendan, et al.
Publicado: (2021)

Simplified Chinese Version of the Spinal Instability Neoplastic Score in Evaluating Patients with Metastatic Spinal Tumor: A Cross‐Cultural Adaptation and Validation
por: Chen, Jiajia, et al.
Publicado: (2022)

MSCs-Derived miR-150-5p-Expressing Exosomes Promote Skin Wound Healing by Activating PI3K/AKT Pathway through PTEN
por: Xiu, Cheng, et al.
Publicado: (2022)

Exosomes promote cetuximab resistance via the PTEN/Akt pathway in colon cancer cells
por: Zhang, S., et al.
Publicado: (2017)

Emerging Exosomes and Exosomal MiRNAs in Spinal Cord Injury
por: Feng, Jia, et al.
Publicado: (2021)

Ubiquitin ligase Triad1 promotes neurite outgrowth by inhibiting MDM2-mediated ubiquitination of the neuroprotective factor pleiotrophin
por: Wu, Chunshuai, et al.
Publicado: (2022)

The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models
por: Carnero, Amancio, et al.
Publicado: (2014)

Dysregulation of PI3K/Akt/PTEN Pathway in Canine Mammary Tumor
por: Kim, Soo-Hyeon, et al.
Publicado: (2021)

MiR-26a-5p enhances cells proliferation, invasion, and apoptosis resistance of fibroblast-like synoviocytes in rheumatoid arthritis by regulating PTEN/PI3K/AKT pathway
por: Huang, Zhengping, et al.
Publicado: (2019)

miR-429 Inhibits Differentiation and Promotes Proliferation in Porcine Preadipocytes
por: Peng, Ying, et al.
Publicado: (2016)

PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice
por: Sun, Chen, et al.
Publicado: (2014)

Percutaneous vertebral-disc plasty for thoracolumbar very severe osteoporotic vertebral compression fractures: A randomized controlled study
por: Jiang, Jiawei, et al.
Publicado: (2022)

lncNALT knockdown ameliorates hypertensive retinopathy via PTEN/PI3K/AKT pathway
por: Kang, Haijun, et al.
Publicado: (2023)

TRIM14 regulates melanoma malignancy via PTEN/PI3K/AKT and STAT3 pathways
por: Chen, Jiangyan, et al.
Publicado: (2021)

Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury
por: Zhao, Rui, et al.
Publicado: (2021)

Effect of evodiamine and berberine on miR-429 as an oncogene in human colorectal cancer
por: Liu, Hong, et al.
Publicado: (2016)

Upregulation of PTEN in Glioma Cells by Cord Blood Mesenchymal Stem Cells Inhibits Migration via Downregulation of the PI3K/Akt Pathway
por: Dasari, Venkata Ramesh, et al.
Publicado: (2010)

PTENP1/miR-20a/PTEN axis contributes to breast cancer progression by regulating PTEN via PI3K/AKT pathway
por: Gao, Xue, et al.
Publicado: (2019)

Exosome miR-371b-5p promotes proliferation of lung alveolar progenitor type II cells by using PTEN to orchestrate the PI3K/Akt signaling
por: Quan, Yuan, et al.
Publicado: (2017)

Patchouli Alcohol Improves the Integrity of the Blood-Spinal Cord Barrier by Inhibiting Endoplasmic Reticulum Stress Through the Akt/CHOP/Caspase-3 Pathway Following Spinal Cord Injury
por: Huang, Chongan, et al.
Publicado: (2021)

PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis
por: Okumura, Naoko, et al.
Publicado: (2012)

Roles of PI3K/AKT/PTEN Pathway as a Target for Pharmaceutical Therapy
por: Matsuda, Satoru, et al.
Publicado: (2013)

PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis
por: Lee, Min-Sik, et al.
Publicado: (2015)

Regulation of the PTEN/PI3K/AKT pathway in RCC using the active compounds of natural products in vitro
por: Wang, Xue, et al.
Publicado: (2021)

miR-382-5p promotes cell invasion in hepatocellular carcinoma by targeting PTEN to activate PI3K/Akt signaling pathway
por: Lv, Bo, et al.
Publicado: (2022)

Cancer‐associated fibroblast‐derived exosomal microRNA‐20a suppresses the PTEN/PI3K‐AKT pathway to promote the progression and chemoresistance of non‐small cell lung cancer
por: Shi, Lin, et al.
Publicado: (2022)

Evaluation of PTEN Inhibitor Following Spinal Cord Injury on Recovery of Voiding Efficiency and Motor Function Observed by Regeneration in Spinal Cord
por: Cho, Young Sam, et al.
Publicado: (2020)

Antioxidant glutathione inhibits inflammation in synovial fibroblasts via PTEN/PI3K/AKT pathway: An in vitro study
por: Ting Hao, Wen, et al.
Publicado: (2021)

miR-494 promotes progression of retinoblastoma via PTEN through PI3K/AKT signaling pathway
por: Xu, Fen, et al.
Publicado: (2020)

Correction: PTENP1/miR-20a/PTEN axis contributes to breast cancer progression by regulating PTEN via PI3K/AKT pathway
por: Gao, Xue, et al.
Publicado: (2023)

NEDD4 promotes cell growth and migration via PTEN/PI3K/AKT signaling in hepatocellular carcinoma
por: Huang, Zhi-Jun, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hfb8c4656uecok0l5p2pt4gm7e