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Unlabeled aspirin as an activatable theranostic MRI agent for breast cancer

Rationale: Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) is emerging as an alternative to gadolinium-based contrast MRI. We have evaluated the possibility of CEST MRI of orthotopic breast tumor xenografts with unlabeled aspirin's conversion to salicylic acid (SA)...

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Detalles Bibliográficos
Autores principales: Pavuluri, KowsalyaDevi, Yang, Ethan, Ayyappan, Vinay, Sonkar, Kanchan, Tan, Zheqiong, Tressler, Caitlin M., Bo, Shaowei, Bibic, Adnan, Glunde, Kristine, McMahon, Michael T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825591/
https://www.ncbi.nlm.nih.gov/pubmed/35198081
http://dx.doi.org/10.7150/thno.53147