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TP53 co-mutations as an independent prognostic factor in 2nd and further line therapy—EGFR mutated non-small cell lung cancer IV patients treated with osimertinib

BACKGROUND: The negative prognostic and predictive value of TP53 co-mutations (TP53 mt+) in EGFR mutated (EGFR mt+) non-small cell lung cancer (NSCLC) is increasingly being acknowledged. Data consistently show that TP53 mt+ impact negatively on 1st line objective response rate (ORR), progression fre...

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Detalles Bibliográficos
Autores principales:	Roeper, Julia, Christopoulos, Petros, Falk, Markus, Heukamp, Lukas C., Tiemann, Markus, Stenzinger, Albrecht, Thomas, Michael, Griesinger, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825660/ https://www.ncbi.nlm.nih.gov/pubmed/35242623 http://dx.doi.org/10.21037/tlcr-21-754

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