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A network-based drug repurposing method via non-negative matrix factorization

MOTIVATION: Drug repurposing is a potential alternative to the traditional drug discovery process. Drug repurposing can be formulated as a recommender system that recommends novel indications for available drugs based on known drug-disease associations. This article presents a method based on non-ne...

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Detalles Bibliográficos
Autores principales: Sadeghi, Shaghayegh, Lu, Jianguo, Ngom, Alioune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8825773/
https://www.ncbi.nlm.nih.gov/pubmed/34875000
http://dx.doi.org/10.1093/bioinformatics/btab826