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Non-orbital Sclerosing Rhabdomyosarcoma Presented With Optic Neuropathy
Sclerosing rhabdomyosarcoma presentations are widely variable and non-specific initial features. We report a rare case of non-orbital sclerosing rhabdomyosarcoma presented with optic neuropathy. A 15-year-old female patient initially presented with upper gum swelling and pain for 3 months. It was as...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826018/ https://www.ncbi.nlm.nih.gov/pubmed/35155025 http://dx.doi.org/10.7759/cureus.21062 |
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author | Hassan, Maizatul Nadia Wan Hitam, Wan Hazabbah Masnon, Nurul Ain Nadarajan, Chandran |
author_facet | Hassan, Maizatul Nadia Wan Hitam, Wan Hazabbah Masnon, Nurul Ain Nadarajan, Chandran |
author_sort | Hassan, Maizatul Nadia |
collection | PubMed |
description | Sclerosing rhabdomyosarcoma presentations are widely variable and non-specific initial features. We report a rare case of non-orbital sclerosing rhabdomyosarcoma presented with optic neuropathy. A 15-year-old female patient initially presented with upper gum swelling and pain for 3 months. It was associated with loosening of teeth. Subsequently, the patient developed recurrent epistaxis follow by left facial swelling and blurring of vision. Examination showed marked left facial swelling with mild proptosis. Visual acuity in the left eye was no perception of light with the presence of relative afferent pupillary defect. Fundoscopy showed left optic atrophy. Neuroimaging showed large aggressive soft tissue mass on the left infratemporal, masticator, and parapharyngeal space with a local extension to the sphenoid sinus. There was also an intracranial extension to the left temporal lobe with the base of skull bone destruction. Transnasal endoscopic biopsy revealed sclerosing rhabdomyosarcoma. Management was with chemotherapy. Sclerosing rhabdomyosarcoma may present with optic nerve involvement that may carry a guarded prognosis to the eyes. |
format | Online Article Text |
id | pubmed-8826018 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-88260182022-02-11 Non-orbital Sclerosing Rhabdomyosarcoma Presented With Optic Neuropathy Hassan, Maizatul Nadia Wan Hitam, Wan Hazabbah Masnon, Nurul Ain Nadarajan, Chandran Cureus Ophthalmology Sclerosing rhabdomyosarcoma presentations are widely variable and non-specific initial features. We report a rare case of non-orbital sclerosing rhabdomyosarcoma presented with optic neuropathy. A 15-year-old female patient initially presented with upper gum swelling and pain for 3 months. It was associated with loosening of teeth. Subsequently, the patient developed recurrent epistaxis follow by left facial swelling and blurring of vision. Examination showed marked left facial swelling with mild proptosis. Visual acuity in the left eye was no perception of light with the presence of relative afferent pupillary defect. Fundoscopy showed left optic atrophy. Neuroimaging showed large aggressive soft tissue mass on the left infratemporal, masticator, and parapharyngeal space with a local extension to the sphenoid sinus. There was also an intracranial extension to the left temporal lobe with the base of skull bone destruction. Transnasal endoscopic biopsy revealed sclerosing rhabdomyosarcoma. Management was with chemotherapy. Sclerosing rhabdomyosarcoma may present with optic nerve involvement that may carry a guarded prognosis to the eyes. Cureus 2022-01-09 /pmc/articles/PMC8826018/ /pubmed/35155025 http://dx.doi.org/10.7759/cureus.21062 Text en Copyright © 2022, Hassan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Ophthalmology Hassan, Maizatul Nadia Wan Hitam, Wan Hazabbah Masnon, Nurul Ain Nadarajan, Chandran Non-orbital Sclerosing Rhabdomyosarcoma Presented With Optic Neuropathy |
title | Non-orbital Sclerosing Rhabdomyosarcoma Presented With Optic Neuropathy |
title_full | Non-orbital Sclerosing Rhabdomyosarcoma Presented With Optic Neuropathy |
title_fullStr | Non-orbital Sclerosing Rhabdomyosarcoma Presented With Optic Neuropathy |
title_full_unstemmed | Non-orbital Sclerosing Rhabdomyosarcoma Presented With Optic Neuropathy |
title_short | Non-orbital Sclerosing Rhabdomyosarcoma Presented With Optic Neuropathy |
title_sort | non-orbital sclerosing rhabdomyosarcoma presented with optic neuropathy |
topic | Ophthalmology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826018/ https://www.ncbi.nlm.nih.gov/pubmed/35155025 http://dx.doi.org/10.7759/cureus.21062 |
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