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Examining the Effect of Kindlin-3 Binding Site Mutation on LFA-1-ICAM-1 Bonds by Force Measuring Optical Tweezers

Integrins in effector T cells are crucial for cell adhesion and play a central role in cell-mediated immunity. Leukocyte adhesion deficiency (LAD) type III, a genetic condition that can cause death in early childhood, highlights the importance of integrin/kindlin interactions for immune system funct...

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Detalles Bibliográficos
Autores principales:	McDonald, Craig, Morrison, Vicky L., McGloin, David, Fagerholm, Susanna Carola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826073/ https://www.ncbi.nlm.nih.gov/pubmed/35154074 http://dx.doi.org/10.3389/fimmu.2021.792813

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