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Pevonedistat Suppresses Pancreatic Cancer Growth via Inactivation of the Neddylation Pathway

BACKGROUND: The neddylation pathway is aberrantly overactivated in multiple human cancers and has been indicated as an effective target for anticancer therapy in clinical trials. We aimed to study whether the neddylation pathway is upregulated in pancreatic cancer and whether pevonedistat, a first-i...

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Detalles Bibliográficos
Autores principales:	Xu, Junfeng, Li, Zheng, Zhuo, Qifeng, Ye, Zeng, Fan, Guixiong, Gao, Heli, Ji, Shunrong, Yu, Xianjun, Xu, Xiaowu, Liu, Wensheng, Xu, Wenyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826241/ https://www.ncbi.nlm.nih.gov/pubmed/35155257 http://dx.doi.org/10.3389/fonc.2022.822039

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