PTBP3 modulates P53 expression and promotes colorectal cancer cell proliferation by maintaining UBE4A mRNA stability

The RNA binding protein PTBP3 was recently reported to play a critical role in multiple cancers, and the molecular mechanisms involved RNA splicing, 3′ end processing and translation. However, the role of PTBP3 in colorectal cancer (CRC) remains poorly explored. Herein, PTBP3 was upregulated in CRC...

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Detalles Bibliográficos
Autores principales: Xie, Canbin, Long, Fei, Li, Liang, Li, Xiaorong, Ma, Min, Lu, Zhixing, Wu, Runliu, Zhang, Yi, Huang, Lihua, Chou, Jing, Gong, Ni, Hu, Gui, Lin, Changwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826374/
https://www.ncbi.nlm.nih.gov/pubmed/35136024
http://dx.doi.org/10.1038/s41419-022-04564-8

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