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DeepMP: a deep learning tool to detect DNA base modifications on Nanopore sequencing data

MOTIVATION: DNA methylation plays a key role in a variety of biological processes. Recently, Nanopore long-read sequencing has enabled direct detection of these modifications. As a consequence, a range of computational methods have been developed to exploit Nanopore data for methylation detection. H...

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Detalles Bibliográficos
Autores principales: Bonet, Jose, Chen, Mandi, Dabad, Marc, Heath, Simon, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria, Lagergren, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826383/
https://www.ncbi.nlm.nih.gov/pubmed/34718417
http://dx.doi.org/10.1093/bioinformatics/btab745

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