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Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material
A Burch–Schneider (BS) cage is a reinforcement device used in total hip arthroplasty (THA) revision surgeries to bridge areas of acetabular loss. There have been a variety of BS cages in the market, which are made of solid metal. However, significant differences in structural configuration and mecha...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826441/ https://www.ncbi.nlm.nih.gov/pubmed/35155392 http://dx.doi.org/10.3389/fbioe.2022.819005 |
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author | Xu, Manman Zhang, Yan Wang, Shuting Jiang, Guozhang |
author_facet | Xu, Manman Zhang, Yan Wang, Shuting Jiang, Guozhang |
author_sort | Xu, Manman |
collection | PubMed |
description | A Burch–Schneider (BS) cage is a reinforcement device used in total hip arthroplasty (THA) revision surgeries to bridge areas of acetabular loss. There have been a variety of BS cages in the market, which are made of solid metal. However, significant differences in structural configuration and mechanical behavior between bone and metal implants cause bone resorption and interface loosening, and hence lead to failure of the implant in the long term. To address this issue, an optimal design framework for a cellular BS cage was investigated in this study by genetic algorithm and topology optimization, inspired by porous human bone with variable holes. In this optimization, a BS cage is constructed with functionally graded lattice material which gradually evolves to achieve better mechanical behavior by natural selection and natural genetics. Clinical constraints that allow adequate bone ingrowth and manufacturing constraint that ensures the realization of the optimized implant are considered simultaneously. A homogenization method is introduced to calculate effective mechanical properties of octet-truss lattice material in a given range of relative density. At last, comparison of the optimum lattice BS cage with a fully solid cage and a lattice cage with identical element density indicates the validity of the optimization design strategy proposed in this article. |
format | Online Article Text |
id | pubmed-8826441 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-88264412022-02-10 Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material Xu, Manman Zhang, Yan Wang, Shuting Jiang, Guozhang Front Bioeng Biotechnol Bioengineering and Biotechnology A Burch–Schneider (BS) cage is a reinforcement device used in total hip arthroplasty (THA) revision surgeries to bridge areas of acetabular loss. There have been a variety of BS cages in the market, which are made of solid metal. However, significant differences in structural configuration and mechanical behavior between bone and metal implants cause bone resorption and interface loosening, and hence lead to failure of the implant in the long term. To address this issue, an optimal design framework for a cellular BS cage was investigated in this study by genetic algorithm and topology optimization, inspired by porous human bone with variable holes. In this optimization, a BS cage is constructed with functionally graded lattice material which gradually evolves to achieve better mechanical behavior by natural selection and natural genetics. Clinical constraints that allow adequate bone ingrowth and manufacturing constraint that ensures the realization of the optimized implant are considered simultaneously. A homogenization method is introduced to calculate effective mechanical properties of octet-truss lattice material in a given range of relative density. At last, comparison of the optimum lattice BS cage with a fully solid cage and a lattice cage with identical element density indicates the validity of the optimization design strategy proposed in this article. Frontiers Media S.A. 2022-01-26 /pmc/articles/PMC8826441/ /pubmed/35155392 http://dx.doi.org/10.3389/fbioe.2022.819005 Text en Copyright © 2022 Xu, Zhang, Wang and Jiang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Xu, Manman Zhang, Yan Wang, Shuting Jiang, Guozhang Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material |
title | Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material |
title_full | Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material |
title_fullStr | Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material |
title_full_unstemmed | Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material |
title_short | Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material |
title_sort | genetic-based optimization of 3d burch–schneider cage with functionally graded lattice material |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826441/ https://www.ncbi.nlm.nih.gov/pubmed/35155392 http://dx.doi.org/10.3389/fbioe.2022.819005 |
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