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Analysis of Eukaryotic lincRNA Sequences Indicates Signatures of Hindered Translation Linked to Selection Pressure

Long intergenic noncoding RNAs (lincRNAs) represent a large fraction of transcribed loci in eukaryotic genomes. Although classified as noncoding, most lincRNAs contain open reading frames (ORFs), and it remains unclear why cytoplasmic lincRNAs are not or very inefficiently translated. Here, we analy...

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Detalles Bibliográficos
Autores principales: Brümmer, Anneke, Dreos, René, Marques, Ana Claudia, Bergmann, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826458/
https://www.ncbi.nlm.nih.gov/pubmed/34897509
http://dx.doi.org/10.1093/molbev/msab356