Solvent directed chemically divergent synthesis of β-lactams and α-amino acid derivatives with chiral isothiourea

A protocol for the chemically divergent synthesis of β-lactams and α-amino acid derivatives with isothiourea (ITU) catalysis by switching solvents was developed. The stereospecific Mannich reaction occurring between imine and C(1)-ammonium enolate generated zwitterionic intermediates, which underwen...

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Detalles Bibliográficos
Autores principales: Ji, Dong-Sheng, Liang, Hui, Yang, Kai-Xuan, Feng, Zhi-Tao, Luo, Yong-Chun, Xu, Guo-Qiang, Gu, Yucheng, Xu, Peng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826511/
https://www.ncbi.nlm.nih.gov/pubmed/35282623
http://dx.doi.org/10.1039/d1sc06127e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826511/
https://www.ncbi.nlm.nih.gov/pubmed/35282623
http://dx.doi.org/10.1039/d1sc06127e

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